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This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
1. Gene and Cell therapy overview.- 2. Gene and Cell therapy history.- 3. Delivery systems for gene therapy.- 4. Stem-cells and tissue regeneration theories.- 5. Gene therapy strategies.- 6. Gene and cell therapy applications.- 7. Gene therapy clinical trials.- 8. Research in gene therapy: celllular and animal models.- 9. Future challenges in gene and cell therapy
